6-Phosphogluconic acid

CAS No. 921-62-0

6-Phosphogluconic acid ( —— )

Catalog No. M26037 CAS No. 921-62-0

6-Phosphogluconic acid is a potent and competitive inhibitor of phosphoglucose isomerase (PGI).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    6-Phosphogluconic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    6-Phosphogluconic acid is a potent and competitive inhibitor of phosphoglucose isomerase (PGI).
  • Description
    6-Phosphogluconic acid is a potent and competitive inhibitor of phosphoglucose isomerase (PGI).The activity of phosphoglucose isomerase was inhibited intensely and competitively by 6-Phosphogluconic acid, with an apparent Ki of 0.048 mM for glucose 6-phosphate and 0.042 mM for fructose 6-phosphate as the substrate.(In Vitro):With glucose 6-phosphate as the substrate, at concentrations from 0.05 to 0.5 mM, the activity of the enzyme was inhibited completely in the presence of 0.5-2.0 mM 6-Phosphogluconic acid. With 0.05-0.2 mM fructose 6-phosphate as the substrate, it was inhibited greater than or equal to 85% at the same concentrations of the inhibitor. No significant changes were observed in the values of Km, Vmax, and Ki for phosphoglucose isomerase in the brain of 6-aminonicotinamide-treated rats.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    921-62-0
  • Formula Weight
    276.1
  • Molecular Formula
    C6H13O10P
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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