6-Phosphogluconic acid
CAS No. 921-62-0
6-Phosphogluconic acid ( —— )
Catalog No. M26037 CAS No. 921-62-0
6-Phosphogluconic acid is a potent and competitive inhibitor of phosphoglucose isomerase (PGI).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Name6-Phosphogluconic acid
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NoteResearch use only, not for human use.
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Brief Description6-Phosphogluconic acid is a potent and competitive inhibitor of phosphoglucose isomerase (PGI).
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Description6-Phosphogluconic acid is a potent and competitive inhibitor of phosphoglucose isomerase (PGI).The activity of phosphoglucose isomerase was inhibited intensely and competitively by 6-Phosphogluconic acid, with an apparent Ki of 0.048 mM for glucose 6-phosphate and 0.042 mM for fructose 6-phosphate as the substrate.(In Vitro):With glucose 6-phosphate as the substrate, at concentrations from 0.05 to 0.5 mM, the activity of the enzyme was inhibited completely in the presence of 0.5-2.0 mM 6-Phosphogluconic acid. With 0.05-0.2 mM fructose 6-phosphate as the substrate, it was inhibited greater than or equal to 85% at the same concentrations of the inhibitor. No significant changes were observed in the values of Km, Vmax, and Ki for phosphoglucose isomerase in the brain of 6-aminonicotinamide-treated rats.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number921-62-0
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Formula Weight276.1
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Molecular FormulaC6H13O10P
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Purity>98% (HPLC)
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Solubility——
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SMILESO[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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